Strombafort is an artificial steroid, similar to testosterone, a naturally occurring steroid.
Strombafort is used to treat hereditary angioedema, which causes episodes of swelling in the face, extremities, genitals, intestinal wall, and throat. Strombaphorth can reduce the frequency and severity of these attacks.
Strombaphorth reduces bradykinin production and could potentially reduce the impact of a bradykinin storm. Bradykinin storms may be responsible for some of the complications experienced by patients with COVID-19.
In rare cases, severe and even fatal liver problems have developed during treatment with Strombaphorto. Contact your doctor immediately if you experience abdominal pain, light-colored stools, dark-colored urine, unusual fatigue, nausea or vomiting, yellowing of the skin or eyes. These may be early signs of liver problems.
Before taking the drug
Do not take Strombaphorto without first talking to your doctor if you have
- prostate cancer;
- breast cancer; or
- an elevated blood calcium level (hypercalcemia).
To be sure that Strombafort is safe for you, tell your doctor if you have ever had an infection:
- heart or blood vessel disease;
- a heart attack;
- an elevated blood cholesterol level;
- bleeding or blood clotting problems;
- liver problems
- kidney problems; or
if you have taken an oral anticoagulant (blood thinner).
You may not be able to take Strombaphorto or may need dosage adjustment or special monitoring during treatment.
Strombaphorth is known to cause birth defects in an unborn baby. Do not take this medication if you are pregnant or may become pregnant during treatment.
It is not known if Strombaphortum passes into breast milk. If you are breastfeeding a baby, do not take this medication without first talking to your doctor.
How should I take Strombafort?
Take Strombafort exactly as directed by your doctor. If you do not understand these instructions, ask your doctor, nurse, or pharmacist to explain them to you.
Take the medication with a full glass of water.
Strombaphor can be taken with or without food.
It is important to take the medication regularly for maximum benefit.
During treatment with this medication, your doctor may require blood tests or other medical evaluations to monitor progress and side effects.
Store at room temperature, away from moisture, heat and direct light.
Usual dose for adults with angioedema:
Prophylactic use to reduce the frequency and severity of hereditary angioedema attacks.
Initial dose: 2 mg orally 3 times daily.
Reduce the dose at 1-3 month intervals to a maintenance dose of 2 mg/day.
What happens if I miss a dose?
Take the missed dose as soon as you remember taking it. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication
What happens in case of an overdose?
An overdose of this medication is unlikely to be life-threatening. If an overdose is suspected, contact an emergency room or poison control center.
Symptoms of a Strombaphorto overdose are not known.
What to avoid
There are no restrictions on food, drink, or activities while taking Strombaphort unless otherwise directed by your doctor.
Side effects of Strombaphort
In rare cases, serious and even fatal liver problems have developed during treatment with Strombafort. Contact your doctor immediately if you experience abdominal pain, light-colored stools, dark-colored urine, unusual fatigue, nausea or vomiting, yellowing of the skin or eyes. These may be early signs of liver problems.
If you experience any of the following serious side effects, contact your doctor immediately or go to an emergency room:
- an allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue or face, or hives);
- swelling of the arms or legs (especially the ankles);
- frequent or persistent erection, tightness or enlargement of the breasts (male patients); or
- changes in voice (hoarseness, deepening), hair loss, facial hair growth, clitoral enlargement, or menstrual irregularities (female patients).
Common side effects of Strombafort may include:
- new or worsening acne;
- difficulty sleeping;
- headaches; or
- changes in sexual desire.
Side effects other than those listed here may also occur. Talk to your doctor about any side effects that seem unusual or are particularly bothersome.
What other medications affect Strombafort?
Before taking Strombafort, consult your doctor if you are taking any of the following medications:
a blood thinner (anticoagulant) such as warfarin (Coumadin); or
insulin or an oral diabetic medication such as glipizide (Glucotrol), glyburide (DiaBeta, Glynase, Micronase), glimepiride (Amaryl), chlorpropamide (Diabinese), acetohexamide (Dymelor), tolbutamide (Orinase), tolazamide (Tolinase), and others.
Dosage adjustment or special monitoring may be needed if you are taking any of the drugs listed above.
Drugs other than those listed may also interact with Strombaphorto. Consult your doctor and pharmacist before taking any prescription or over-the-counter medications, including vitamins, minerals, and herbal products.
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